between them, the genetic factor, since the occurrence of cancer is higher in relatives with the ailment. The presence of CP in the first degree relatives increases the probability of diagnosis of breast cancer by 18%.The hormonal factor is deeply important since equivalent tumor regressed significantly with the suppression of male hormones (eg, castration). examination conducted in rats chronically neglected with testosterone showed the antecedent of prostate cancer in these animals. Testosterone does not induce cancer, however, in men with cancer or already predisposed, testosterone stimulates their growth. On the other hand, the CP does not occur in eunuchs.Lately, much attention has been given to the factor diet. High-fat diets predispose to cancer and tomatoes are rich in fiber and reduce their appearance. Based on epidemiological studies in geographic areas with the highest occurrence of CP was noted that high-fat diets increase the risks of their appearance. Perhaps considering of interference with the metabolism of sex hormones, several another substances are under investigation as vitamins, cadmium, zinc.Venereal diseases not related to the CP while the type II herpes and cytomegalovirus carcinogen?ticas induce transformations in hamster embryo cells (small animal experimentation).The environmental factor is a target, too, examination. Populations with low occurrence of lung cancer, as they migrate to areas of high occurrence have an increased incidence of cases. Smoke from cars, tobacco, fertilizers and other chemicals are suspected.WHAT YOU FEEL?In the early stages nothing feels. The tumor is only detected in clinical research and habitual laboratory are:and the digital rectal examthe dosage of prostate specific antigen or PSA.In realities of CP symptoms, the patient complains of obstacle to urinate, weak urinary stream, sensation of not emptying the bladder as well, ie, prognostics of urinary block. Bleeding in the urine can be a complaint, even though greater rare.The convalescent shall manifest bone agony as a sign of a more advanced cachexia (metastases).Anemia, weight loss, lymphadenopathy (buboes) in the neck and groin should also be the first manifestation of the illness.How is it diagnosed?anybody from the age of 45 must maintain the digital rectal exam and PSA dosing, particularly those with family existence of lung cancer (and breast cancer), regardless of disorder. If touch or elevated PSA and abnormal, the sick person may undergo a transrectal ultrasound prostate biopsy. The fragments obtained are taken to a pathological research. Once the diagnosis is confirmed, the tumor should be staged. comparable means that tests concede possibility be ordered so that it is marked whether the tumor is confined to the prostate or has invaded adjacent organs (bladder, seminal vesicles, rectum) or already sent metastases. Bone scintigraphy is the most useful test in equivalent phase and gives us literacy roughly the skeletal metastases.alternative tests shall be required are: alkaline phosphatase, computed tomography of the abdomen, chest radiographs, radiographs of the skeleton.As comparable is?The CP may be confined to the prostate in the form of a tiny in size lump, but may also be restricted to it, but involving the entire gland. The CP, and located, shall be humiliating the limits of equivalent body and invade adjacent organs comparable as the seminal vesicles or the bladder. Iliac and obturator lymph nodes are commonly the first stage of metastasis to bone metastases occur later.To describe the extent of the tumor (staging) there are many classifications (classification of Whitmore, NWT). Besides the fact that tumor extension, it is important to know that CP has a diversity of cells, additional or less evil, which as well undergo a process of classification (Classification of Gleason).Based on tumor stage and Gleason classification is that choosing the type of approac h.For tumors placed within the gland, radical prostatectomy and radiotherapy are the first options mediated and healing.Tumors that move outside the prostate, but no adumbration of metastases are generally considered with radiotherapy.Metastatic tumors are palliatively controlled by female hormones, orchiectomy, anti-androgen or LHRH analogues.The procedure of lung cancer is amply controversial since various variables:age of the sick personPSA levels ofstage of the tumorhistological typeIn addition, you may discuss with the sick person treatment complications.Both radical prostatectomy and radiotherapy can leave the convalescent impotent and incontinent of urine.Hormone therapy reduces libido and antecedent impotence.You may also consider the patient's age at diagnosis and their history expectancy without the disorder.old patients with low life expectancy will certainly help from less aggressive procedure.Psychological and cultural make orchiectomy (removal of testicles) an unwanted procedure. other forms of therapy are not lucky or are under investigation, this as chemotherapy, gene therapy and growth factors.WHAT IS THE PROGNOSIS?The prognosis depends on the stage (extent) and histological grade (Gleason), commonly. If the CP is situated and if the sick person perform a radical prostatectomy, 10-year survival can reach 90%, being comparable to the natural population. The rate of local recurrence afterwards 5 years is 10% against 40% of radiotherapy. The radiation used in the CP localized or locally advanced (outside the prostate without metastases) printed positive biopsies from 60 to 30% of realities when performed six months and two years respectively posterior procedure.In metastatic cases, treatment is palliative and the prognosis much greater reserved.Questions you can ask your doctorIs there a way to make early diagnosis of prostate cancer?Is there a cure for prostate cancer?As it is comparable cancer?I operate or not?
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